Open AccessCulture-Expanded Autologous Adipose-Derived Mesenchymal Stem Cell Treatment for Osteonecrosis of the Femoral Head
Author(s) -
Pil Whan Yoon,
Jung Mook Kang,
Chul Ho Kim,
Soong Joon Lee,
Jeong Joon Yoo,
Hee Joong Kim,
Sung Keun Kang,
Ju Hyeon Min,
Kang Sup Yoon
Publication year - 2021
Publication title -
clinics in orthopedic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.002
H-Index - 34
eISSN - 2005-4408
pISSN - 2005-291X
DOI - 10.4055/cios20128
Subject(s) - medicine , femoral head , magnetic resonance imaging , harris hip score , womac , mesenchymal stem cell , surgery , transplantation , femur , liposuction , radiology , arthroplasty , osteoarthritis , pathology , alternative medicine
Outcomes of traditional treatment for osteonecrosis of the femoral head (ONFH) are not always satisfactory. Hence, cell-supplementation therapy has been attempted to facilitate necrotic-tissue regeneration. Adipose-derived mesenchymal stem cell (ADMSC) transplantation is potentially advantageous over bone marrow-derived MSC implantation, but its outcomes for ONFH remain unclear. The aim of this study was to determine 2-year radiological and clinical outcomes of culture-expanded autologous ADMSC implantation for ONFH.