Open AccessIncreased Melanoma-Associated Antigen C2 Expression Affords Resistance to Apoptotic Deathin Suspension-Cultured Tumor Cells
Author(s) -
Doyeon Park,
Sora Han,
Hyunjeong Joo,
Hye In Ka,
Sujung Soh,
Jiyoung Park,
Young Yang
Publication year - 2021
Publication title -
journal of breast cancer/journal of breast cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 36
eISSN - 2092-9900
pISSN - 1738-6756
DOI - 10.4048/jbc.2021.24.e6
Subject(s) - stat3 , apoptosis , cancer research , stat protein , cell cycle , oncogene , annexin , cell growth , microbiology and biotechnology , biology , flow cytometry , biochemistry , genetics
Melanoma-associated antigen C2 (MAGEC2) is an oncogene associated with various types of cancers. However, the biological function of MAGEC2 in circulating tumor cells remains unclear. In this study, we investigated the role of MAGEC2 using adapted suspension cells (ASCs), which were previously developed to study circulating tumor cells (CTCs).