Open AccessClinical, Imaging, and Laboratory Markers of Premanifest Spinocerebellar Ataxia 1, 2, 3, and 6: A Systematic Review
Author(s) -
Dong Hoi Kim,
Ryul Kim,
Jee Young Lee,
Kyoung Min Lee
Publication year - 2021
Publication title -
journal of clinical neurology/the journal of clinical neurology
Language(s) - English
Resource type - Journals
eISSN - 2005-5013
pISSN - 1738-6586
DOI - 10.3988/jcn.2021.17.2.187
Subject(s) - spinocerebellar ataxia , ataxia , medicine , physical medicine and rehabilitation , psychology , neuroscience
Premanifest mutation carriers with spinocerebellar ataxia (SCA) can exhibit subtle abnormalities before developing ataxia. We summarized the preataxic manifestations of SCA1, -2, -3, and -6, and their associations with ataxia onset.