Open AccessRapid Virologic Response to Brincidofovir in Children with Disseminated Adenovirus Infection
Author(s) -
Shuk Ying Chan,
Susan E. Prockop,
Farid Boulad,
Genovefa A. Papanicolaou,
Yeon Joo Lee
Publication year - 2021
Publication title -
infection and chemotherapy/gam'yeom gwa hwahag yo'beob/infection and chemotherapy
Language(s) - English
Resource type - Journals
eISSN - 2092-6448
pISSN - 1598-8112
DOI - 10.3947/ic.2020.0204
Subject(s) - medicine , cidofovir , adenovirus infection , virology , hematopoietic cell , immunology , haematopoiesis , virus , stem cell , biology , genetics
Disseminated adenovirus infections (d-ADV) after hematopoietic cell transplant (HCT) are often fatal with limited treatment options. Brincidofovir (BCV) a lipid ester of cidofovir is developed for this indication. We report four pediatric HCT recipients with d-ADV treated successfully with BCV.