Open AccessE. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung‑associated enterocolitis via activation of TLR4/p‑p38/NF‑κB signaling
Author(s) -
Zebing Zheng,
Mingjuan Gao,
Chengyan Tang,
Lu Huang,
Yuanyuan Gong,
Yuanmei Liu,
Jian Wang
Publication year - 2022
Publication title -
molecular medicine reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.727
H-Index - 56
eISSN - 1791-3004
pISSN - 1791-2997
DOI - 10.3892/mmr.2022.12684
Subject(s) - knockout mouse , biology , tlr4 , oncogene , enterocolitis , microbiology and biotechnology , cancer research , hirschsprung's disease , signal transduction , nfkb1 , apoptosis , gene knockout , molecular medicine , p38 mitogen activated protein kinases , cell cycle , medicine , receptor , transcription factor , gene , genetics , mapk/erk pathway , disease