Open AccessKLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS‑induced ATDC5 cells via SIRT1/NF‑κB/p53 signaling
Author(s) -
Xi Chen,
Jia Wen,
Chaoqi Liu,
Donggeng Guo
Publication year - 2022
Publication title -
molecular medicine reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.727
H-Index - 56
eISSN - 1791-3004
pISSN - 1791-2997
DOI - 10.3892/mmr.2022.12680
Subject(s) - klf4 , sirtuin 1 , oxidative stress , transcription factor , microbiology and biotechnology , biology , fgf21 , inflammation , tumor necrosis factor alpha , apoptosis , signal transduction , blot , cancer research , downregulation and upregulation , immunology , endocrinology , fibroblast growth factor , biochemistry , receptor , sox2 , gene