Open AccessTotal saponin of Dioscorea�collettii attenuates MSU crystal‑induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase‑1 in THP‑1 macrophages
Author(s) -
Lu Wang,
Li-Ran Zhu,
Chenfangyuan Duan,
Lü Li,
Guangliang Chen
Publication year - 2020
Publication title -
molecular medicine reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.727
H-Index - 56
eISSN - 1791-3004
pISSN - 1791-2997
DOI - 10.3892/mmr.2020.11035
Subject(s) - nalp3 , inflammasome , thp1 cell line , caspase 1 , proinflammatory cytokine , inflammation , apoptosis , tumor necrosis factor alpha , interleukin , chemistry , microbiology and biotechnology , biology , cytokine , immunology , biochemistry , cell culture , genetics