Open AccessIdentification ofalkAgene related to virulence ofShigella flexneri 2aby mutational analysis
Author(s) -
Zhonghua Shi
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i12.2720
Subject(s) - shigella flexneri , virulence , biology , shigella , plasmid , mutant , gene , microbiology and biotechnology , homologous recombination , genetics , escherichia coli
In vivo induced genes are thought to play an important role during infection of host. AlkA was identified as an in vivo-induced gene by in vivo expression technology (IVET), but its virulence in Shigella flexneri was not reported. The purpose of this study was to identify the role of alkA gene in the pathogenesis of S. flexneri.