Open AccessStereotactic radiotherapy and the potential role of magnetic resonance-guided adaptive techniques for pancreatic cancer
Author(s) -
Tai Ermongkonchai,
Richard Khor,
Vijayaragavan Muralidharan,
Niall C. Tebbutt,
Kelvin O. Lim,
Numan Kutaiba,
Sweet Ping Ng
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i7.745
Subject(s) - medicine , pancreatic cancer , radiation therapy , magnetic resonance imaging , radiology , chemoradiotherapy , malignancy , cancer , radiosurgery
Pancreatic cancer is a malignancy with one of the poorest prognoses amongst all cancers. Patients with unresectable tumours either receive palliative care or undergo various chemoradiotherapy regimens. Conventional techniques are often associated with acute gastrointestinal toxicities, as adjacent critical structures such as the duodenum ultimately limits delivered doses. Stereotactic body radiotherapy (SBRT) is an advanced radiation technique that delivers highly ablative radiation split into several fractions, with a steep dose fall-off outside target volumes.