Open AccessGastric mucosal precancerous lesions in Helicobacter pylori-infected pediatric patients in central China: A single-center, retrospective investigation
Author(s) -
Yu Ming,
Ma Jing,
Xin Song,
QiaoQiao Shao,
XueChun Yu,
Muhammad Noman Khan,
YaBin Qi,
RuoBing Hu,
PeiRu Wei,
Xiao Wei,
Bing Ji,
Yanbo Cheng,
Lingfei Kong,
Chuanliang Chen,
SongZe Ding
Publication year - 2022
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v28.i28.3682
Subject(s) - medicine , helicobacter pylori , gastroenterology , intestinal metaplasia , rapid urease test , atrophic gastritis , gastritis , cancer , population , pathological , dysplasia , chronic gastritis , gastric mucosa , stomach , environmental health
Helicobacter pylori ( H. pylori ) infects about 50% of the world population and is the major cause of chronic gastritis, peptic ulcers, and gastric cancer. Chronic H. pylori infection induces gastric mucosal precancerous lesions mostly in adulthood, and it is debatable whether these pathological conditions can occur in childhood and adolescents as well. Since this is a critical issue to determine if intervention should be offered for this population group, we investigated the gastric mucosal precancerous lesions in pediatric patients in an area in central China with a high prevalence of H. pylori and gastric cancer.