Open AccessChanges in gut microbiota composition and diversity associated with post-cholecystectomy diarrhea
Author(s) -
Yandong Li,
Bao-Ning Liu,
Zhao Song,
Yinghao Zhou,
Liang Bai,
Enqi Liu
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i5.391
Subject(s) - gut flora , firmicutes , bacteroidetes , prevotella , biology , diarrhea , lactobacillus , feces , cholecystectomy , microbiome , bifidobacterium , microbiology and biotechnology , medicine , immunology , 16s ribosomal rna , bacteria , genetics
Post-cholecystectomy diarrhea (PCD) frequently occurs in patients following gallbladder removal. PCD is part of the post-cholecystectomy (PC) syndrome, and is difficult to treat. After cholecystectomy, bile enters the duodenum directly, independent of the timing of meals. The interaction between the bile acids and the intestinal microbes is changed. Therefore, the occurrence of PCD may be related to the change in microbiota. However, little is known about the relationship between the gut microbiota and PCD.