Open AccessAutosomal recessive 333 base pair interleukin 10 receptor alpha subunit deletion in very early-onset inflammatory bowel disease
Author(s) -
Jiajia Lv,
Wenyu Su,
Xiaoyan Chen,
Yi Yu,
Xu Xu,
Chun-Di Xu,
Xing Wang Deng,
Jiaoling Huang,
Xinqiong Wang,
Xiao Ming Yuan
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i44.7705
Subject(s) - peripheral blood mononuclear cell , medicine , inflammatory bowel disease , exome sequencing , exon , gastroenterology , immunology , biology , disease , mutation , gene , genetics , in vitro
Interleukin 10 receptor alpha subunit (IL10RA) dysfunction is the main cause of very early-onset inflammatory bowel disease (VEO-IBD) in East Asians.