
Metal-organic framework IRMOFs coated with a temperature-sensitive gel delivering norcantharidin to treat liver cancer
Author(s) -
Xiuyan Li,
Qingxia Guan,
Yu-Zhou Shang,
Yanhong Wang,
Shaowa Lv,
Zhengming Yang,
Rui Wang,
Yukuan Feng,
Weinan Li,
Yongji Li
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i26.4208
Subject(s) - liver cancer , medicine , cancer , chemistry , cancer research
Norcantharidin (NCTD) is suitable for the treatment of primary liver cancer, especially early and middle primary liver cancer. This compound can reduce tumors and improve immune function. However, the side effects of NCTD have limited its application. There is a marked need to reduce the side effects and increase the efficacy of NCTD.