Open AccessPPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
Author(s) -
Rui-Nan Zhang,
Feng Shen,
Qin Pan,
Hongyan Cao,
Guangyu Chen,
JianGao Fan
Publication year - 2021
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v27.i25.3863
Subject(s) - nonalcoholic fatty liver disease , ppargc1a , medicine , gastroenterology , odds ratio , steatohepatitis , steatosis , population , fatty liver , biology , disease , genetics , gene , environmental health , coactivator , transcription factor
The association between PPARGC1A rs8192678 and nonalcoholic fatty liver disease (NAFLD) requires further confirmation. In addition, it is still unknown whether PPARGC1A rs8192678 is associated with hepatic histological features in NAFLD in the Chinese population.