Open AccessExosomal miR-182 regulates the effect of RECK on gallbladder cancer
Author(s) -
Hong Zheng,
Jinjing Wang,
Leilei Zhao,
Xiaorong Yang,
Yu Yu
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i9.933
Subject(s) - gallbladder cancer , gallbladder , cancer research , microrna , cancer , medicine , exosome , biology , microvesicles , oncology , gene , biochemistry
As the most common biliary malignancy, gallbladder cancer (GC) is an elderly-biased disease. Although extensive studies have elucidated the molecular mechanism of microRNA 182 (miR-182) and reversion-inducing-cysteine-rich protein with kazal motifs (RECK) in various cancers, the specific role of exosomal miR-182 and RECK in GC remains poorly understood.