Open AccessTuberous sclerosis patient with neuroendocrine carcinoma of the esophagogastric junction: A case report
Author(s) -
Natsuki Ishida,
Takahiro Miyazu,
Satoshi Tamura,
Satoshi Suzuki,
Shinya Tani,
Mihoko Yamade,
Moriya Iwaizumi,
Satoshi Osawa,
Yasushi Hamaya,
Kazuya Shinmura,
Haruhiko Sugimura,
Katsutoshi Miura,
Takahisa Furuta,
Ken Sugimoto
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i45.7263
Subject(s) - esophagogastric junction , tuberous sclerosis , medicine , neuroendocrine carcinoma , carcinoma , gastroesophageal junction , pathology , gastroenterology , oncology , adenocarcinoma , cancer
Tuberous sclerosis complex (TSC) is a rare inherited disease with non-cancerous tumor growths in the skin, brain, kidneys, heart, and lungs. The co-occurrence of neuroendocrine neoplasm (NEN) with TSC is even rarer. There have been few reports on the relationship between TSC and neuroendocrine tumors (NETs), and fewer on the relationship between TSC and neuroendocrine carcinoma (NEC), a subtype of NEN. This is the first reported case of NEC occurring at the esophagogastric junction in a patient with TSC.