Open AccessPromising xenograft animal model recapitulating the features of human pancreatic cancer
Author(s) -
Jinxin Miao,
Jianyao Wang,
Haoze Li,
Han Guo,
Louisa S. Chard,
Zhongxian Zhang,
Zhenguo Cheng,
Dongling Gao,
Jianzeng Dong,
Zhong-De Wang,
Yaohe Wang
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i32.4802
Subject(s) - pancreatic cancer , cancer research , medicine , animal model , cancer , pathology , biology , oncology , computational biology
Multiple sites of metastasis and desmoplastic reactions in the stroma are key features of human pancreatic cancer (PC). There are currently no simple and reliable animal models that can mimic these features for accurate disease modeling.