Open AccessMetabolite profile comparisons between ascending and descending colon tissue in healthy adults
Author(s) -
Bridget A. Baxter,
Kristopher D. Parker,
Michael J. Nosler,
Sangeeta Rao,
R. Bruce Craig,
Catherine Seiler,
Elizabeth P. Ryan
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i3.335
Subject(s) - metabolome , colorectal cancer , overweight , metabolite , metabolomics , descending colon , body mass index , medicine , ascending colon , physiology , cancer , endocrinology , gastroenterology , biology , bioinformatics , rectum
Obesity is a risk factor for colorectal cancer, yet metabolic distinctions between healthy right and left colon tissue, before cancer is diagnosed, remains largely unknown. This study compared right-ascending and left-descending colon tissue metabolomes to identify differences from the stool metabolome in normal weight, overweight, and obese adults.