Open AccessDNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p
Author(s) -
Tao Xu,
Ting Lei,
Si-Qiao Li,
Erhui Mai,
Feihu Ding,
Ben Niu
Publication year - 2020
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v26.i15.1745
Subject(s) - oncogene , flow cytometry , gene silencing , biology , cancer research , downregulation and upregulation , viability assay , mtt assay , apoptosis , pancreatic cancer , competing endogenous rna , microbiology and biotechnology , western blot , long non coding rna , cancer , cell cycle , gene , genetics
The incidence and mortality rates of pancreatic carcinoma (PC) are rapidly increasing worldwide. Long noncoding RNAs (lncRNAs) play critical roles during PC initiation and progression. Since the lncRNA DNAH17-AS1 is highly expressed in PC, the regulation of DNAH17-AS1 in PC was investigated in this study.