Open AccessDynamic changes of key metabolites during liver fibrosis in rats
Author(s) -
Jiong Yu,
Jianqin He,
Deying Chen,
Qiaoling Pan,
Jinfeng Yang,
Cao H,
Lanjuan Li
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i8.941
Subject(s) - fibrosis , medicine , masson's trichrome stain , pathology , receiver operating characteristic , hepatic fibrosis , biomarker , liver function tests , gastroenterology , biology , biochemistry
Fibrosis is the single most important predictor of significant morbidity and mortality in patients with chronic liver disease. Established non-invasive tests for monitoring fibrosis are lacking, and new biomarkers of liver fibrosis and function are needed.