Open AccessInsulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation via activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer
Author(s) -
Baishun Wan,
Ming Cheng,
Ling Zhang
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i40.6063
Subject(s) - protein kinase b , microrna , cancer research , pancreatic cancer , insulin like growth factor binding protein , cell growth , messenger rna , growth factor , insulin like growth factor , cancer , biology , signal transduction , chemistry , medicine , microbiology and biotechnology , gene , biochemistry , receptor
Studies have shown that insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) plays critical roles in the genesis and development of human cancers.