Open AccessNested case-control study on risk factors for opportunistic infections in patients with inflammatory bowel disease
Author(s) -
Shan-Shan Gong,
YiMing Fan,
Qingqing Han,
Bin Lv,
Yi Xu
Publication year - 2019
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v25.i18.2240
Subject(s) - medicine , incidence (geometry) , inflammatory bowel disease , odds ratio , opportunistic infection , immunology , case control study , calprotectin , clostridium difficile , epidemiology , disease , viral disease , antibiotics , virus , biology , physics , microbiology and biotechnology , optics
When opportunistic infections occur, patients with inflammatory bowel disease (IBD) commonly display a significantly increased rate of morbidity and mortality. With increasing use of immunosuppressive agents and biological agents, opportunistic infections are becoming a hot topic in the perspective of drug safety in IBD patients. Despite the well-established role of opportunistic infections in the prognosis of IBD patients, there are few epidemiological data investigating the incidence of opportunis-tic infections in IBD patients in China. Besides, the risk factors for opportunistic infection in Chinese IBD patients remain unclear.