Open Accessβ-arrestin 2 attenuates lipopolysaccharide-induced liver injuryviainhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice
Author(s) -
Mengping Jiang,
Chun Xu,
Yi Guo,
Qian-Jiang Luo,
Li Lin,
Huiling Liu,
Jie Jiang,
Huixin Chen,
Xiuqing Wei
Publication year - 2018
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v24.i2.216
Subject(s) - tlr4 , lipopolysaccharide , tumor necrosis factor alpha , liver injury , inflammation , proinflammatory cytokine , signal transduction , in vivo , nf κb , cytokine , pharmacology , biology , immunology , chemistry , microbiology and biotechnology
To study the role and the possible mechanism of β-arrestin 2 in lipopolysaccharide (LPS)-induced liver injury in vivo and in vitro .