Open AccessInvestigation of mitigating effect of colon-specific prodrugs of boswellic acid on 2,4,6-trinitrobenzene sulfonic acid-induced colitis in Wistar rats: Design, kinetics and biological evaluation
Author(s) -
Ajinkya Pradeep Sarkate,
Suneela Dhaneshwar
Publication year - 2017
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v23.i7.1147
Subject(s) - prodrug , chemistry , pharmacology , colitis , in vivo , bioavailability , stomach , gastrointestinal tract , biochemistry , gastroenterology , medicine , biology , microbiology and biotechnology
To develop a colon-targeting bioreversible delivery system for β-boswellic acid (BBA) and explore utility of its prodrugs in 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats.