Open AccessQinggan Huoxue Recipe suppresses epithelial-to-mesenchymal transition in alcoholic liver fibrosis through TGF-β1/Smad signaling pathway
Author(s) -
Tao Wu,
Junming Chen,
Tiegang Xiao,
Xiangbing Shu,
Hanchen Xu,
Lili Yang,
Lianjun Xing,
Peiyong Zheng,
Guang Ji
Publication year - 2016
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v22.i19.4695
Subject(s) - smad , epithelial–mesenchymal transition , vimentin , fibronectin , occludin , western blot , endocrinology , transforming growth factor , chemistry , medicine , biology , microbiology and biotechnology , immunohistochemistry , biochemistry , extracellular matrix , tight junction , cancer , gene , metastasis
To investigate the mechanism by which Qinggan Huoxue Recipe (QGHXR) inhibits epithelial-to-mesenchymal transition (EMT) in rats with alcoholic liver fibrosis (ALF).