Open AccessPhosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948
Author(s) -
WenSheng Huang,
Tianbao Wang,
Yi He,
Yu-Jun Chen,
Shilong Zhong,
Min Tong
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i26.3458
Subject(s) - microbiology and biotechnology , transfection , biology , lipofectamine , cell growth , cell cycle , phosphoinositide 3 kinase , gene expression , flow cytometry , cell , apoptosis , protein kinase b , gene , recombinant dna , biochemistry , vector (molecular biology)
To investigate the gene knock-down effect by the phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA)-targeted double-stranded RNA (dsRNA) and its effect on cell proliferation and cycle distribution in SW948.