Open AccessHBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module
Author(s) -
Renxian Tang,
Fanyun Kong,
Baochao Fan,
Xiaomei Liu,
Hua You,
Peng Zhang,
Kuiyang Zheng
Publication year - 2012
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v18.i13.1485
Subject(s) - hbx , transfection , apoptosis , fas ligand , microbiology and biotechnology , signal transduction , kinase , biology , chemistry , programmed cell death , cell culture , biochemistry , genetics
To investigate the possible mechanism by which hepatitis B virus X protein (HBx) mediates apoptosis of HepG2 cells.