Open AccessLong-term effects of lamivudine treatment in Japanese chronic hepatitis B patients
Author(s) -
Masayuki Murata,
Norihiro Furusyo,
Mami Unno,
Eiichi Ogawa,
Kazuhiro Toyoda,
Hiroaki Taniai,
Hiroyuki Ohnishi,
Jun Hayashi
Publication year - 2011
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v17.i24.2945
Subject(s) - lamivudine , medicine , adefovir , gastroenterology , hepatitis b virus , virology , hepatitis b , virus
To analyze the association between the emergence of tyrosine-methionine-asparatate-asparatate (YMDD) mutants (reverse transcription; rtM204I/V) and deterioration of liver function during long-term lamivudine treatment of Japanese patients with chronic hepatitis B virus (HBV) infection.