Open AccessImpaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats
Author(s) -
Jinming Han,
Xiaoming Zhan,
Xinyu Li,
Bing Xia,
Yueying Wang,
Jing Zhang,
Baoxin Li
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i48.6111
Subject(s) - protein kinase b , pi3k/akt/mtor pathway , endocrinology , medicine , tunel assay , apoptosis , biology , mitochondrion , phosphorylation , fatty liver , signal transduction , chemistry , biochemistry , disease
to determine whether mitochondrial dysfunction resulting from high-fat diet is related to impairment of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt, also known as PKB) pathway.