Open AccessPaclitaxel ameliorates fibrosis in hepatic stellate cellsviainhibition of TGF-β/Smad activity
Author(s) -
Jun Zhou,
Di Zhong,
Qunwei Wang,
Xiangshui Miao,
Xun-Di Xu
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i26.3330
Subject(s) - hepatic stellate cell , paclitaxel , smad , fibronectin , hepatic fibrosis , extracellular matrix , transforming growth factor , fibrosis , transforming growth factor beta , cell culture , blot , chemistry , medicine , cancer research , biology , biochemistry , chemotherapy , genetics , gene
To investigated if paclitaxel can attenuate hepatic fibrosis in rat hepatic stellate cells (RHSCs).