Open AccessThiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease
Author(s) -
Xianwen Dong
Publication year - 2010
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v16.i25.3187
Subject(s) - thiopurine methyltransferase , inflammatory bowel disease , medicine , gastroenterology , toxicity , pharmacogenetics , incidence (geometry) , disease , genotype , biology , gene , genetics , physics , optics
To evaluate the relationship between thiopurine S-methyltransferase (TPMT) polymorphisms and thiopurine-induced adverse drug reactions (ADRs) in inflammatory bowel disease (IBD).