Open AccessElucidation of the relationship of BNIP3 expression to gemcitabine chemosensitivity and prognosis
Author(s) -
Masaharu Ishida,
Makoto Sunamura,
Toru Furukawa,
Masanori Akada,
Hiroko Fujimura,
Emiko Shibuya,
Shinichi Egawa,
Michiaki Unno,
Akira Horii
Publication year - 2007
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v13.i34.4593
Subject(s) - gemcitabine , pancreatic cancer , oncology , medicine , immunohistochemistry , cancer , cancer research , biology
To evaluate the significance of BNIP3 in the pathogenesis of pancreatic cancer, we analyzed the relationship between the expression of BNIP3 and survival rate of the patients with pancreatic cancer, or chemosensitivities in pancreatic cancer cell lines, particularly for gemcitabine, the first-line anti-tumor drug for pancreatic cancer.