Open AccessChemokine expression in hepatocellular carcinoma versus colorectal liver metastases
Author(s) -
Claudia Rubie,
Vilma Oliveira Frick,
Mathias Wagner,
Christina Weber,
B. Kruse,
Katja Kempf,
Jochen König,
Bettina Rau,
Martin K. Schilling
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i41.6627
Subject(s) - ccl20 , c c chemokine receptor type 6 , chemokine receptor , c c chemokine receptor type 7 , cxcr4 , hepatocellular carcinoma , cancer research , carcinogenesis , metastasis , chemokine , medicine , pathology , receptor , cancer
To evaluate and compare the expression profiles of CXCL12 (SDF-1), CCL19 (MIP-3beta), CCL20 (MIP-3alpha) and CCL21 (6Ckine, Exodus2) and their receptors on RNA and protein levels in hepatocellular carcinoma (HCC) versus colorectal liver metastases (CRLM) and to elucidate their impact on the carcinogenesis and progression of malignant liver diseases.