Open AccessGastric cancer in a Caucasian population: Role of pepsinogen C genetic variants
Author(s) -
A.L. Pinto-Correia,
Hugo Sousa,
Maria Fragoso,
Luís MoreiraDias,
Carlos Lopes,
Rui Medeiros,
Mário DinisRibeiro
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i31.5033
Subject(s) - allele , intestinal metaplasia , biology , stomach , population , allele frequency , cancer , gastroenterology , pathology , medicine , genetics , gene , environmental health
To study the role of an insertion/deletion polymorphism in the pepsinogen C (PGC) gene, an effective marker for terminal differentiation of the stomach mucosa, in the susceptibility to the development of gastric lesions.