Open AccessEffects of adenoviral-mediated gene transduction of NK4 on proliferation, movement, and invasion of human colonic LS174T cancer cells in vitro
Author(s) -
Jian-Zheng Jie,
Jianwei Wang,
Junle Qu,
Wei Wang,
Tao Hung
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i25.3983
Subject(s) - hepatocyte growth factor , cancer research , cell culture , biology , viral vector , cell growth , in vitro , genetic enhancement , recombinant dna , cell migration , adenoviridae , gene , receptor , biochemistry , genetics
To investigate the inhibitory effects of a recombinant adenovirus vector that expresses NK4, a truncated form of human hepatocyte growth factor (HGF), on human colonic adenocarcinoma cells in vitro to establish a basis for future NK4 gene cancer therapy.