Open AccessUp-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury
Author(s) -
Lauren M. Aleksunes,
Michael Goedken,
José E. Manautou
Publication year - 2006
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v12.i12.1937
Subject(s) - western blot , liver injury , nad+ kinase , immunohistochemistry , acetaminophen , enzyme , chemistry , pharmacology , microbiology and biotechnology , biology , biochemistry , medicine , immunology , gene
To investigate the expression and activity of NAD(P)H quinone oxidoreductase 1 (NQO1) in human liver specimens obtained from patients with liver damage due to acetaminophen (APAP) overdose or primary biliary cirrhosis (PBC).