Open AccessExtraintestinal manifestations in inflammatory bowel disease
Author(s) -
Silvio Danese,
S Semeraro,
Alfredo Papa,
I. Roberto,
Franco Scaldaferri,
G. Fedeli,
Giovanni Gasbarrini,
Antonio Gasbarrini
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i46.7227
Subject(s) - medicine , ulcerative colitis , inflammatory bowel disease , disease , organ system , crohn's disease , inflammatory bowel diseases , gastroenterology , multisystem disease , dermatology
Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a new clinical challenge every day, worsened by the very frequent rate of extraintestinal complications. The goal of this review is to provide an overview and an update on the extraintestinal complications occurring in IBD. Indeed, this paper highlights how virtually almost every organ system can be involved, principally eyes, skin, joints, kidneys, liver and biliary tracts, and vasculature (or vascular system) are the most common sites of systemic IBD and their involvement is dependent on different mechanisms.