Open AccessHigh concentrations of human β-defensin 2 in gastric juice of patients withHelicobacter pyloriinfection
Author(s) -
Hajime Isomoto
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i31.4782
Subject(s) - helicobacter pylori , beta defensin , gastritis , defensin , gastric mucosa , antrum , helicobacter , spirillaceae , immune system , medicine , gastroenterology , stomach , immunology , chemistry , biology , microbiology and biotechnology , antimicrobial , innate immune system
Human beta-defensin (HBD)-1 and HBD-2 are endogenous antimicrobial peptides. Unlike HBD-1, the HBD-2 expression is augmented by Helicobacter pylori (H pylori). We sought to determine HBD-1 and HBD-2 concentrations in gastric juice during H pylori infection.