Open AccessTetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion secretion in distal colon of rodents
Author(s) -
Qiong He,
Jinxia Zhu,
Ying Xing,
Lai-Ling Tsang,
Ning Yang,
Dewi K. Rowlands,
YiuWa Chung,
Hsiao-Chang Chan
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i27.4173
Subject(s) - forskolin , dids , ibmx , cystic fibrosis transmembrane conductance regulator , chemistry , amiloride , channel blocker , glibenclamide , apical membrane , medicine , endocrinology , biochemistry , biology , receptor , sodium , organic chemistry , membrane , diabetes mellitus , gene , calcium
To investigate the effect of tetramethylpyrazine (TMP), an active compound from Ligustium Wollichii Franchat, on electrolyte transport across the distal colon of rodents and the mechanism involved.