Open AccessOrnithine decarboxylase gene is overexpressed in colorectal carcinoma
Author(s) -
Haiyan Hu
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i15.2244
Subject(s) - ornithine decarboxylase , microbiology and biotechnology , subcloning , biology , monoclonal antibody , immunohistochemistry , messenger rna , blot , colorectal cancer , gene expression , antibody , cancer research , gene , cancer , recombinant dna , immunology , enzyme , biochemistry , genetics
To investigate the ornithine decarboxylase (ODC) gene expression in colorectal carcinoma, ODC mRNA was assayed by RT-PCR and ODC protein was detected by a monoclonal antibody against fusion of human colon ODC prepared by hybridoma technology.