Open AccessThe protective mechanism of Yisheng Injection against hepatic ischemia reperfusion injury in mice
Author(s) -
Feng Cheng,
Youping Li,
Jingqiu Cheng,
Feng Li,
Shengfu Li
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i8.1198
Subject(s) - reperfusion injury , lactate dehydrogenase , ischemia , myeloperoxidase , medicine , malondialdehyde , pharmacology , proinflammatory cytokine , in vivo , liver transplantation , oxidative stress , alanine transaminase , transplantation , immunology , inflammation , chemistry , enzyme , biochemistry , biology , microbiology and biotechnology
Hepatic ischemia/reperfusion injury may cause acute inflammatory, significant organ damage or dysfunction, and remains an important problem for liver transplantation. Our previous in vivo and in vitro studies demonstrated that Yisheng injection (YS), a traditional Chinese medicine, had protective effect on ischemia/reperfusion injury. In this study, we examined whether YS had protective effect for hepatic ischemia/reperfusion injury and explored its protective mechanism.