Open AccessTime- and pH-dependent colon-specific drug delivery for orally administered diclofenac sodium and 5-aminosalicylic acid
Author(s) -
Gang Cheng,
Feng An,
Meijuan Zou,
Jin Sun,
Xiuhua Hao,
Yue He
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i12.1769
Subject(s) - enteric coating , aminosalicylic acid , pellets , dosage form , diclofenac sodium , chemistry , in vivo , pharmacology , drug delivery , absorption (acoustics) , diclofenac , antacid , controlled release , coating , chromatography , materials science , medicine , biochemistry , organic chemistry , microbiology and biotechnology , composite material , biology
To investigate Time- and pH-dependent colon-specific drug delivery systems (CDDS) for orally administered diclofenac sodium (DS) and 5-aminosalicylic acid (5-ASA), respectively.