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The existence and uniqueness of solutions for a coupled system of Liouville–Caputo type fractional integro-differential equations with multi-point and sub-strip boundary conditions are investigated in this study. The fractional integro-differential equations contain a finite number of Riemann–Liouville fractional integral and non-integral type nonlinearities, as well as Caputo differential operators of various orders subject to fractional boundary conditions on an infinite interval. At the boundary conditions, we use sub-strip and multi-point contribution. There are various techniques to solve such type of differential equations and one of the most common is known as symmetry analysis. The symmetry analysis has widely been used in problems involving differential equations, although determining the symmetries can be computationally intensive compared to other methods. Therefore, we employ the degree theory due to the Mawhin involving measure of a non-compactness technique to arrive at our desired findings. An interesting pertinent problem has also been provided to demonstrate the applicability of our results.

Study of a Coupled System with Sub-Strip and Multi-Valued Boundary Conditions via Topological Degree Theory on an Infinite Domain