Open AccessUpregulation of MicroRNA-34a Sensitizes Ovarian Cancer Cells to Resveratrol by Targeting Bcl-2
Author(s) -
Shangli Yao,
Ming Gao,
Zujun Wang,
Wenyan Wang,
Lei Zhan,
Bing Wei
Publication year - 2021
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2021.62.8.691
Subject(s) - downregulation and upregulation , resveratrol , microrna , ovarian cancer , cancer research , cancer , medicine , chemistry , biology , pharmacology , biochemistry , gene
Resveratrol (REV), a natural compound found in red wine, exhibits antitumor activity in various cancers, including ovarian cancer (OC). However, its potential anti-tumor mechanisms in OC are not well characterized. Here, we tried to elucidate the underlying mechanisms of REV in OC cells.