
Effect and Mechanism Study of Sodium Houttuyfonate on Ventilator-Induced Lung Injury by Inhibiting ROS and Inflammation
Author(s) -
Yi Liu,
Gang Tang,
Jinyu Li
Publication year - 2021
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2021.62.6.545
Subject(s) - reactive oxygen species , apoptosis , inflammation , proinflammatory cytokine , lung , chemistry , mechanical ventilation , pharmacology , medicine , immunology , anesthesia , biochemistry
Ventilator-induced lung injury (VILI) is a serious complication of mechanical ventilation (MV) that increases morbidity and mortality of patients receiving ventilator treatment. This study aimed to reveal the molecular mechanism of sodium houttuyfonate (SH) on VILI.