Open AccessBasiliximab Induction with Delayed Calcineurin Inhibitors for High-Risk Lung Transplant Candidates
Author(s) -
Ha Eun Kim,
Hyo Chae Paik,
Su Jin Jeong,
Moo Suk Park,
Song Yee Kim,
Jin Gu Lee
Publication year - 2021
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2021.62.2.164
Subject(s) - basiliximab , calcineurin , medicine , lung transplantation , induction therapy , tacrolimus , lung , pharmacology , urology , transplantation , chemotherapy
Calcineurin inhibitor (CNI) use has improved lung transplantation outcomes. However, significant perioperative complications in patients receiving CNI can deteriorate the early course of lung transplantation. To date, there is no consensus regarding the optimal agent for the induction regimen after lung transplantation. We aimed to determine the efficacy of basiliximab induction with delayed CNI initiation in the prevention of acute complications without compromising immunosuppression in high-risk patients.