Open AccessComparison of Different Types of Oral Adsorbent Therapy in Patients with Chronic Kidney Disease: A Multicenter, Randomized, Phase IV Clinical Trial
Author(s) -
Youn Kyung Kee,
Sang Youb Han,
Duk Hee Kang,
Jung Woo Noh,
Kyung Hwan Jeong,
Gheun-Ho Kim,
Yang Wook Kim,
Beom Seok Kim
Publication year - 2021
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2021.62.1.41
Subject(s) - medicine , renal function , kidney disease , gastroenterology , creatinine , cystatin c , adverse effect , dialysis , randomized controlled trial
Oral adsorbents delay disease progression and improve uremic symptoms in patients with chronic kidney disease (CKD). DW-7202 is a newly developed oral adsorbent with high adsorptive selectivity for uremic toxins. We evaluated patient preference for and adherence to DW-7202 versus AST-120 therapy and compared treatment efficacy and safety in patients with pre-dialysis CKD.