Open AccessRenormalization of Thalamic Sub-Regional Functional Connectivity Contributes to Improvement of Cognitive Function after Liver Transplantation in Cirrhotic Patients with Overt Hepatic Encephalopathy
Author(s) -
Ying-Sheng Cheng,
Jingyuan Li,
Jia-Min Zhou,
Gao-Yan Zhang,
Wen Shen,
Xiaodong Zhang
Publication year - 2021
Publication title -
korean journal of radiology/korean journal of radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.08
H-Index - 57
eISSN - 2005-8330
pISSN - 1229-6929
DOI - 10.3348/kjr.2020.1432
Subject(s) - medicine , liver transplantation , hepatic encephalopathy , thalamus , neuropsychology , cognition , transplantation , prefrontal cortex , gastroenterology , cirrhosis , radiology , psychiatry
The role of preoperative overt hepatic encephalopathy (OHE) in the neurophysiological mechanism of cognitive improvement after liver transplantation (LT) remains elusive. This study aimed to explore changes in sub-regional thalamic functional connectivity (FC) after LT and their relationship with neuropsychological improvement using resting-state functional MRI (rs-fMRI) data in cirrhotic patients with and without a history of OHE.