Open AccessSynthesis of Polymeric (Self-Disappearing) Nano Medical Patches Loaded with a Long-Acting Pharmacological Substance by Electrospinning Method
Author(s) -
Alia Hindi,
Mohammad Yahia Masri,
S. Hardcastle,
M.A. Batal
Publication year - 2021
Publication title -
nanotechnology and applications
Language(s) - English
Resource type - Journals
ISSN - 2639-9466
DOI - 10.33425/2639-9466.1029
Subject(s) - scanning electron microscope , materials science , nano , polymer , electrospinning , diclofenac , nanofiber , nanotechnology , chemical engineering , drug delivery , composite material , biomedical engineering , polymer science , medicine , pharmacology , engineering
Nano-polymer (self-disappearing) medical patches loaded with a long-acting drug were manufactured by cospinning method of synthetic polymers PVA and PVP at a rate of 10%W for each polymer and with the addition different medicinal substances, namely diclofenac de ethylamine, gentamicin, in concentration 5%w (each substance separately). And studding the morphological structure of the prepared samples by scanning electron microscope (SEM) and X- Ray diffraction (XRD), then converted into a medical adhesive form, and then tested on the human hand directly, as it has proven its effectiveness in delivering the drug to the affected area directly. It is very easy to use, medically safe and economic, as it does not need huge industrial equipment for its production.