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The purpose of this study is to investigate serial changes of hypoxia-inducible factor 1α (HIF-1α), as a key regulator of hypoxic ischemia, and apoptosis of hippocampus induced by bilateral carotid arteries occlusion (BCAO) in rats.

Serial Expression of Hypoxia Inducible Factor-1α and Neuronal Apoptosis in Hippocampus of Rats with Chronic Ischemic Brain